June 23, 2007

Worst Fears Realized In S. Africa TB Scare

Of the 45 samples, 10 were resistant to all six TB drugs they tested for.

"I got a cold shiver, with such fear in my heart," Moll said. "I thought, 'This is airborne. Could I be infected? Could my staff be infected?' To go into a new realm of XDR-TB, which is basically untreatable, was almost unthinkable," he said, using the acronym for Extremely Drug-Resistant Tuberculosis.

Moll's worst fears eventually were realized: Four of the hospital nurses died in those first few months. From that point on, the hospital began identifying more and more patients — and in almost all cases, the patients with XDR-TB were dead before the lab results were back. Most die within 16 days of being identified as a possible XDR-TB case. The mortality rate of XDR-TB is 84 percent.

...

"Ultimately we need prevention, as the current treatment regime just isn't the way to go," Moll said. "The bulk of the patients just die so quickly."

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